Microbiota News
Structured summaries of the scientific literature, updated daily.
Dietary Modulation of Gut Microbiome in High Cholesterol Diet–Induced Atherosclerosis
In a rabbit model of cholesterol-induced atherosclerosis, a cornstarch diet significantly suppressed serum TMAO and hepa…
Resistant starch diet in prediabetes: protocol for a multicentre randomised controlled trial
This paper describes only the protocol of an ongoing RCT testing an optimised carbohydrate diet (~40 g/day resistant sta…
Probiotic supplementation increases fecal TLR4 agonists without improving disease activity in juvenile idiopathic arthritis: a randomized placebo-controlled trial
VSL#3 for 3 months failed to improve clinical responses in children with juvenile idiopathic arthritis and, under worst-…
Global research trends in enteric nervous system and gut microbiota: a bibliometric analysis (2005–2025)
A bibliometric analysis of 759 publications maps growth patterns and thematic foci in the ENS–microbiota field from 2005…
Gut microbiome, dietary patterns, and cognition: bMicrobiome sub-study protocol
This paper describes the development of a readiness-to-change nutritional habits survey integrated with gut microbiome p…
Probiotics and synbiotics in MASLD/NAFLD: meta-analysis of 30 RCTs
Probiotics and synbiotics reduced ALT, AST, and TNF-α in MASLD/NAFLD patients, with limited effect on triglycerides and …
Perioperative probiotics and bone healing in tibial shaft fracture: a randomized controlled trial
A double-blind RCT assessed whether perioperative Lactobacillus rhamnosus GG plus Bifidobacterium longum affects CT-meas…
Gut microbiota-derived TMAO and atrial fibrillation: meta-analysis
Elevated circulating TMAO levels are significantly associated with atrial fibrillation risk, with a pooled OR of 1.35 (9…
Probiotic supplementation in combat sports athletes during weight reduction: body composition, lipid profiles, and fatty acid metabolism
Four weeks of probiotic supplementation was associated with greater body fat reduction and altered fatty acid metabolism…
Natural products and exercise-induced fatigue: systematic review on gut microbiota modulation
A systematic review of 26 studies — 25 animal, 1 human — identifies the SCFA-AMPK/PGC-1α axis as a shared mechanism acro…
Early-life stress and adolescent circadian dysrhythmia drive unique behavioral and microbial profiles in rats
Combined maternal separation and circadian disruption during adolescence impaired risk assessment behavior and produced …
Natural products as modulators of age-associated gut microbiota dysbiosis: a systematic review of animal models
A systematic review of 17 animal studies suggests natural products normalise gut microbiota in ageing models, with assoc…
Circadian rhythms as regulators of the gut-brain-immune axis: implications for neuroinflammation and neurodegeneration
Narrative review examines how circadian rhythms modulate gut microbiota and the immune system, with proposed repercussio…
Recent advances and clinical relevance of microbiome dynamics in health and disease
Narrative review synthesizes evidence on the human microbiome's role across multiple organ systems and current therapeut…
Faecal Microbiota Transplantation Reduces Lesion Severity and Medication Use in Canine Atopic Dermatitis: A Randomised, Placebo-Controlled, Double-Blinded Clinical Trial
Adjunctive oral and rectal FMT reduced skin lesion severity scores and symptomatic medication use in dogs with atopic de…
Gut reservoir of carbapenem-resistant Enterobacterales: from dysbiosis and colonization to infection and decolonization in hematologic malignancy patients
This narrative review synthesizes evidence linking gut dysbiosis to CRE colonization persistence and invasive infection,…
Dealcoholized muscadine wine improved skin elasticity and oxidative stress biomarkers without affecting gut microbiome in women over 40
Daily intake of 300 mL dealcoholized muscadine wine for 6 weeks improved selected skin elasticity parameters and reduced…
Probiotics in preterm infants: meta-analysis on neonatal jaundice and respiratory distress syndrome
Probiotic supplementation was significantly associated with reduced neonatal jaundice and respiratory distress syndrome …
Isolation of folate-producing probiotics and regulatory effects on homocysteine metabolism and gut microbiota composition
Isolated folate-producing probiotic strains reduced serum homocysteine and altered gut microbiota in folate-deficient mi…
Gut microbiota and response to multimodal therapy in hepatocellular carcinoma with portal vein tumor thrombus
Baseline and longitudinal gut microbial signatures were associated with therapeutic response in HCC patients with PVTT r…
Gut Dysbiosis, Serine-Glycine Metabolism, and Glioblastoma: Therapeutic Opportunities
A narrative review proposes that gut microbiota alterations modulate serine/glycine metabolism and may influence gliobla…
Gut microbiome modulation by Bacillus coagulans BCP92 in healthy subjects: randomized double-blind placebo-controlled clinical trial
B. coagulans BCP92 supplementation for 42 days did not produce major changes in gut microbiota composition in healthy in…
Metagenomics-Guided Personalized Synbiotic Protocol in Children with ASD: An Exploratory Case Series
Seven children with ASD received individualized metagenomics-guided synbiotics, with caregiver-reported improvements in …
Polyphenols, gut microbiota and cognitive function: a narrative review
A narrative review examines the role of polyphenols in cognition and dementia through gut-microbiota-brain axis modulati…
Emotional Eating and Abdominal Obesity: Narrative Review of Mechanisms and Emerging Interventions
A narrative review maps physiological and behavioral mechanisms linking emotional eating to visceral fat accumulation.
Ginseng Bioactive Components as Gut-Brain Axis Modulators: Therapeutic Potential in Multifactorial Diseases
Narrative review maps mechanisms by which ginseng ginsenosides, polysaccharides, and polyphenols act on the gut-brain ax…
Compound acid chemical peeling in moderate acne: split-face trial with microbiome and inflammatory evaluation
Six sessions of compound acid peeling reduced clinical acne scores, cutaneous inflammatory markers, and altered facial m…
Depression and anxiety in inflammatory bowel disease: mechanisms and emerging therapeutics targeting the microbiota-gut-brain axis
Narrative review maps bidirectional mechanisms between IBD and psychiatric disorders, reporting 35.7% anxiety and 15.7% …
Celiac disease and gut microbiota: bibliometric mapping of research hotspots and immune-mechanistic trends
A bibliometric analysis documents growing scientific output on celiac disease and gut microbiota without producing new e…
Gut microbiota mediates repeated sevoflurane-induced cognitive impairment via the gut-brain axis
Repeated sevoflurane exposure in neonatal rats altered gut microbiota composition and elevated systemic and hippocampal …
Gut dysbiosis induces PTSD-like behaviors via LPS-microglial activation; ACPC restores synaptic expression in mice
Gut microbiota dysbiosis promotes LPS-mediated microglial activation and PTSD-like behavior in mice, partially reversed …
Gut Microbiota Mediates Repeated Sevoflurane-Induced Cognitive Impairment via the Gut-Brain Axis
Repeated sevoflurane exposure impaired cognition in neonatal rats and altered gut microbiota, effects partially reversed…
Postbiotic cocktail attenuates DSS-induced colitis in mice via autophagy pathway modulation
Postbiotics from Limosilactobacillus spp. and Bifidobacterium spp. reduced experimental colitis markers and upregulated …
Baseline gut microbiome ecology predicts long-term fat mass loss after bariatric surgery: evidence for a thrifty Bifidobacterium phenotype
High baseline Bifidobacterium spp. levels are associated with reduced fat mass loss at 24 months after bariatric surgery…
2'-Fucosyllactose modulates gut microbiota and systemic metabolism in mild-to-moderate ulcerative colitis: a randomized crossover trial
2'-FL supplementation significantly increased Bifidobacterium abundance and altered fecal metabolite profiles, but showe…
Effect of postbiotics on biofilm formation and gene expression in Candida spp. isolates from patients with recurrent vulvovaginal candidiasis
Cell-free supernatants from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus inhibited Candida spp. biofilm fo…
Efficacy and safety of H. pylori eradication therapy in real-world clinical practice: results of the PAMIR observational program
A Russian real-world observational program assessed H. pylori eradication with standard triple therapy and augmented reg…
Yeast-derived postbiotic fermentate (EpiCor®) modulates inflammatory cytokines in healthy adults: double-blind crossover trial
A single 500-mg dose of EpiCor® selectively reduced pro-inflammatory cytokines and transiently redistributed immune cell…
Microbiota-Endometriosis Axis: An Immune-Endocrine Integration Model and Emerging Therapeutic Targets
A narrative review proposes an integrative model in which gut, vaginal, and endometrial microbiota dysbiosis modulates i…
Heat-killed Mycobacterium aurum reduces hyperglycemia in streptozotocin-induced diabetic mice
Both prophylactic oral and therapeutic intradermal administration of heat-killed M. aurum attenuated hyperglycemia in an…
BALIMONT Synbiotic/Postbiotic Composition for Increasing IgA: Clinical Evidence and Translational Interpretation
This document does not present a completed clinical trial with the BALIMONT formulation; it integrates retained technica…
Clinical Efficacy of the Postbiotic Biodonatum in Children with Pneumonia and Reduced Antibiotic Sensitivity
A pediatric RCT evaluates Biodonatum as an adjunct to antibiotic therapy in community-acquired pneumonia with documented…
Amuc_1100 alleviates HFD-induced hepatic lipid accumulation in zebrafish via gut microbiota and intestinal 14-3-3β/α-A protein
The Akkermansia muciniphila outer membrane protein Amuc_1100 reduced high-fat diet-induced hepatic lipid accumulation in…
Microbiomics: Novel Biomarkers of Colorectal Cancer Diagnosis and Prognosis
A narrative review maps gut microorganisms and metabolites as candidate diagnostic and prognostic biomarkers in colorect…
Akkermansia muciniphila and intestinal stem cells: what the review reports
A narrative review compiles evidence on A. muciniphila's ability to modulate intestinal stem cell proliferation and diff…
Dietary fat alters goblet cell function and microbial bile acid metabolism to promote intestinal lipid absorption in mice
Excess dietary lipids impair goblet cell glutamine metabolism, thin the colonic mucus layer, reshape microbiota composit…
Oxidative Stress and Gut-Skin Axis Dysbiosis in Immune-Mediated Skin Disorders: Narrative Review
Elevated oxidative biomarkers and gut dysbiosis are consistently reported across major immune-mediated dermatoses, but c…
Akkermansia muciniphila in metabolic disorders: PRISMA-screened narrative review
A review of 43 reports suggests A. muciniphila supplementation improves insulin resistance, body weight, fat mass, and c…
Polyphenols, gut microbiota and short-chain fatty acids: meta-analysis of RCTs
Polyphenol supplementation significantly increased fecal butyrate concentrations (SMD = 0.48) across 50 RCTs in adults.
Gene-environment interactions in celiac disease: the role of the intestinal epithelium
The intestinal epithelium functions as an active interface integrating genetic susceptibility and environmental signals …
Vitamin D Deficiency in Pregnancy Is Associated With Greater LDL-C Rise, Elevated β-Hydroxybutyrate, and Altered Neonatal Metabolic Markers
Pregnant women with vitamin D deficiency showed steeper LDL-C increases and higher β-hydroxybutyrate levels during gesta…
Akkermansia muciniphila: from unknown bacterium to promising probiotic
Narrative review associates A. muciniphila administration with improved biochemical profiles and reduced inflammation in…
Epigenetic regulation by gut microbiota-derived metabolites in celiac disease
A narrative review maps how microbiota metabolites — especially butyrate — modulate epigenetic mechanisms in celiac dise…
Radiotherapy in Head and Neck Cancers: Oral Microbiota Shifts, Complications, and Management Strategies
Radiotherapy for head and neck cancers induces oral dysbiosis marked by reduced microbial diversity and expansion of pat…
Plantain flour noodles with wheat gluten and phosphate: technological properties and in vitro gut microbiota effects
Adding wheat gluten (≥17.5%) and compound phosphate improves the technological quality of plantain noodles and raises re…
Mechanistic pathways linking gut microbial metabolites to mitochondrial function
A systematic review identifies four microbial metabolite classes with moderate-certainty evidence for direct effects on …
Faecal microbiota transplantation for acute lower GI graft-versus-host disease: Cochrane review protocol
This document is solely a Cochrane review protocol — no efficacy or safety data have been collected or analysed.
Effect of Acute Ketone Monoester Ingestion on Psychomotor Vigilance During Acute Severe Hypoxia
Ketone monoester ingestion attenuated the hypoxia-induced decline in mean reaction time during simulated high-altitude e…
Bibliometric trends in IBS and gut microbiome research: cross-database analysis
Scientific output on IBS and the gut microbiome grew from fewer than 10 articles per year before 2010 to 162 in 2025, wi…
Eight-week synbiotic supplementation in children with MASLD: randomized controlled trial
An 8-week synbiotic intervention produced statistically significant reductions in BMI, triglycerides, total cholesterol,…