Microbiota News
Structured summaries of the scientific literature, updated daily.
Effects of Bifidobacterium animalis subsp. lactis CP-9 on gut microbiota and immune functions in healthy infants
Three-month CP-9 supplementation increased intestinal Bifidobacterium abundance and improved stool characteristics in he…
The skin microbiome: the overlooked axis in modern dermatology
Narrative editorial concludes that the cutaneous microbiome is relevant to skin disease, but current associations are pr…
Effects of probiotic supplementation on gut barrier function in combat athletes during pre-competition weight loss
A 4-week complex probiotic supplementation reduced gut permeability markers and systemic inflammation in combat athletes…
Chitosan supplementation and lifestyle changes in Icelandic women with obesity: effects on health and gut microbiota
Chitosan supplementation reduced the Firmicutes/Bacteroidota ratio, but no differentially abundant taxa were identified;…
Gut microbiome biomarkers for colorectal cancer detection: systematic review highlighting age as a key confounder
Diagnostic performance of gut microbiome biomarkers for colorectal cancer is significantly moderated by age differences …
Probiotics for atopic dermatitis prevention in infants: meta-analysis finds no significant protective effect
A meta-analysis of 18 RCTs with 10,195 participants found no statistically significant reduction in atopic dermatitis ri…
Autoprobiotic supplements attenuate obesity and improve gut microbiota and metabolism in metabolic syndrome: a pilot trial
Autologous Enterococcus faecium and E. hirae supplementation reduced HbA1c and triglycerides compared to control in meta…
Expert Consensus on Coriolus versicolor Vaginal Gel for HPV-Positive Women with Low-Grade Cervical Lesions
A multidisciplinary expert panel reached formal consensus that a Coriolus versicolor-based vaginal gel may increase lesi…
Sex- and gender-specific differences in efficacy and safety of traditional Chinese medicine: a scoping review
A scoping review found only 16 studies addressing sex/gender differences in traditional Chinese medicine interventions, …
Localized prebiotic nitrate supplementation remodels oral biofilm metabolism and reduces gingival inflammation: a randomized placebo-controlled trial
Localized nitrate application for 21 days reduced bleeding on probing from 25.7% to 15.3% in adults with gingival inflam…
Phytonutrient-enriched prebiotic mixture enhances probiotic effects: ex vivo screening and human clinical trial
Combining a phytonutrient-enriched prebiotic mixture with probiotics produced greater increases in butyrate and total SC…
Microbiota-epigenome axis: microbial metabolites as modulators of host gene expression
A narrative review maps how gut microbiota-derived metabolites — SCFAs, urolithins, and phenolic acids — modulate host e…
Selenium, gut microbiota, and systemic health: narrative review of the Se-gut-tissue axis
A narrative review proposes that dietary selenium modulates gut microbiota composition and, through this pathway, may in…
Grapevine branch-leaf silage in Kazakh ram diets: growth performance, serum biochemistry, and rumen microbiota
Replacing 50% of corn silage with grapevine branch-leaf silage maximized daily gain and feed intake in Kazakh rams, alon…
Dietary L-Citrulline Supplementation Promotes Rumen Development and Modulates the Microbiota-Metabolome Axis in Suckling Hu Lambs
L-citrulline at 2 g/day improved rumen morphometry, starter intake, and volatile fatty acid profile in suckling lambs, w…
A Kidney-Microbiome Short- and Medium-Chain Fatty Acid Loop Mediated by OAT1: Implications for the Remote Sensing and Signaling Theory
Renal transporter OAT1 forms a bidirectional feedback loop with gut microbiota through short- and medium-chain fatty aci…
Genistein attenuates ovalbumin-induced food allergy in mice: intestinal barrier, gut microbiota, and metabolites
Genistein pretreatment reduced experimental food allergy signs in mice, with associated changes in gut microbiota and fe…
Microbial metabolite butyrate activates sensory neurons through colonic serotonin release in a microfluidic co-culture model
A microfluidic tri-culture model was developed to investigate butyrate-driven serotonin-mediated signaling between colon…
Transcutaneous auricular vagus nerve stimulation in major depressive disorder: brain-gut interaction mechanisms
A registered RCT in 80 patients with MDD used multimodal assessment—rs-fMRI and gut metagenomics—to investigate taVNS br…
Yeast culture promotes butyrate-producing fibrolytic bacteria as intracellular hydrogen sinks in the rumen
Yeast culture supplementation (1%) improved body weight gain, fiber digestibility, and ruminal pH in starch-fed lambs, w…
Gut commensal Odoribacter splanchnicus attenuates hyperlipidemic periodontitis via gut-oral metabolic transmission of β-GPA
Depletion of Odoribacter splanchnicus in the gut is associated with hyperlipidemic periodontitis, and its repletion or s…
Gut Microbiota Modulation Attenuates Myocardial Ischemia-Reperfusion Injury in Diabetic Mice
Fecal microbiota transplantation from lean donors reduced myocardial infarct size in diabetic mice subjected to ischemia…
Resistant starch and polydextrose exert distinct effects on bile acid profiles in healthy adults
Resistant starch supplementation raised conjugated plasma bile acids, while polydextrose reduced secondary bile acid tra…
Heat-treated Lactiplantibacillus plantarum LM1004: microbiome modulation and NK cell activity in a randomized clinical trial
Eight weeks of HT-LM1004 supplementation significantly increased NK cell activity and white blood cell counts compared t…
Cost-effectiveness of Commercial or Traditional Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection
Colonoscopy-delivered FMT is the dominant cost-effective strategy for rCDI; FDA-approved commercial microbiota therapeut…
Separated moxibustion in rheumatoid arthritis: clinical efficacy and gut microbiota modulation
Adding separated moxibustion to conventional drug therapy was associated with improvements in RA clinical scores and neg…
Del-Immune V and microbiome restructuring in colorectal cancer surgery: a randomized double-blind placebo-controlled trial
Perioperative supplementation with Del-Immune V (a L. rhamnosus-derived metabiotic) significantly reduced IL-6 and alter…
Gut Microbiota in Colorectal Cancer: Mechanistic Insights, Clinical Strategies, and a Regional Perspective Focused on Sichuan, China
Narrative review outlines proposed mechanisms linking gut microbiota to colorectal carcinogenesis, with a regional focus…
Gut Microbiome in HIV Pathogenesis: Dysbiosis, Immune Dysfunction, and Viral Persistence
Narrative review synthesizes evidence that gut dysbiosis in HIV infection perpetuates systemic inflammation, impairs imm…
Gut microbiota at high altitude: microbial remodeling, immunity, and adaptation
A systematic review describes how high-altitude environments restructure gut microbiota and modulate immune responses vi…
Interaction of dietary polyphenols and gut microbiota: microbial metabolism, influence, and implications for host health
Narrative review examines the bidirectional relationship between dietary polyphenols and gut microbiota, covering microb…
Washed microbiota transplantation (WMT) in children with ASD: efficacy and donor-recipient microbial characteristics
WMT produced statistically significant improvement in core symptoms, sleep disturbances, and gastrointestinal symptoms i…
Ultrasound-assessed abdominal fat distribution and sarcopenia parameters in community-dwelling young older adults
VAT was positively associated with muscle mass indices, while SAT was negatively associated with physical performance an…
Dupilumab and skin microbiome shifts in Netherton syndrome: case report and literature review
In a single patient with Netherton syndrome, dupilumab was associated with increased cutaneous microbial diversity over …
Fecal microbiota transplantation for post-surgical chronic constipation in an elderly patient: case report
A single elderly patient with refractory chronic constipation and surgically altered bowel anatomy showed symptomatic re…
Oral Microbial and Metabolic Alterations in Patients With Oral Lichen Planus Concomitant With Type 2 Diabetes Mellitus
Patients with co-occurring oral lichen planus and type 2 diabetes show reduced salivary alpha diversity, elevated Pseudo…
Heat-inactivated Lacticaseibacillus paracasei fermented milk (postbiotic) did not outperform placebo for functional constipation
A 4-week double-blind RCT found no significant between-group difference in any primary or secondary clinical outcome for…
Probiotic supplementation and gut microbiota in children with autism: a pilot randomised controlled trial
A pilot RCT in 23 children with ASD found no significant changes in gut microbiota diversity following four months of mu…
Branched-chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapy
Adolescents with severe obesity show elevated serum BCAAs but reduced BCKAs, a pattern distinct from obese adults who ex…
Bacterial bioremediation of metal-contaminated soils in Sub-Saharan Africa: systematic review
A systematic review identifies Bacillus and Pseudomonas as the predominant genera in bacterial bioremediation of mining-…
Effects of Probiotic-Phytonutrient Blends on Defecation, Intestinal Barrier Function, and Gut Microbiota: A Randomized, Placebo-Controlled Trial
Two probiotic-phytonutrient formulations improved stool consistency and increased fecal SCFAs compared to placebo over 8…
Gut Microbiota Composition and Plasma Metabolomic Profile Associated with Amyloid Pathology and Cognitive Performance in MCI Patients
In 47 MCI patients, higher amyloid burden and worse cognitive performance were associated with distinct gut microbiota a…
RCT Protocol on Pectin Supplementation in MASLD: Systemic Inflammation, Gut Microbiome, and Metabolic Health
This abstract describes a trial protocol only — no efficacy results are available.
CaHMB supplementation during caloric restriction in adults with obesity: a randomized controlled trial
Calcium beta-hydroxy-beta-methylbutyrate (CaHMB) supplementation preserved skeletal muscle mass over 12 weeks of energy …
Strain-Specific Effects of Early-Life Probiotic Supplementation on Respiratory Infections in Infants: A Systematic Review and Meta-Analysis
Probiotic or synbiotic supplementation in the first 24 months of life did not significantly reduce the risk of upper res…
Rifaximin plus probiotics reshape gut microbiota, serum propionate and mucosal immunity in cirrhosis-related hepatic encephalopathy
Adding a multistrain probiotic to rifaximin was associated with a graded reduction in serum ammonia and hepatic encephal…
Efficacy of probiotic and synbiotic supplementation on metabolic and endocrine parameters in PCOS: a meta-analysis of RCTs
Probiotic and synbiotic supplementation significantly reduced fasting insulin, total testosterone, triglycerides, LDL-c,…
Natural polysaccharides and depression: systematic review of preclinical evidence via the microbiota-gut-brain axis
A systematic review of 20 preclinical studies associates natural polysaccharides with improved depression-like behaviors…
IBS is associated with small fibre pathology in fibromyalgia patients
Greater IBS severity in fibromyalgia patients correlates with reduced intraepidermal nerve fibre density and higher over…
Lactiplantibacillus plantarum WJL ameliorates adverse effects of low-protein diet in chronic kidney disease via FGF21 modulation
Low-protein diet improves metabolic markers in CKD but triggers a FGF21 adaptive stress response; Lactiplantibacillus pl…
Biovigilance in Faecal Microbiota Transplantation: 7-Year Cohort Study and Framework for Microbiological Assessments of Infectious Adverse Events
Serious adverse reactions attributable to FMT occurred in 1.9% of procedures for recurrent C. difficile infection, with …
Decolonisation of multidrug-resistant E. coli and vancomycin-resistant E. faecium following faecal microbiota transplantation
A single case report describes decolonisation of two multidrug-resistant pathogens via capsulated FMT, followed by acqui…
Adipose tissue-derived stem cell exosomes improve skin barrier and show exploratory associations with skin mycobiome in aging skin
Transdermal delivery of adipose-derived stem cell exosomes significantly reduced transepidermal water loss and improved …
Sodium oligomannate (GV-971) attenuates post-stroke cognitive impairment by restoring intestinal butyrate metabolism
In a murine ischemic stroke model, GV-971 favored cognition and restored butyrate-producing bacteria, but causal evidenc…
Phosphorus availability modulates cucumber susceptibility to Fusarium wilt through rhizosphere metabolite-microbial community interactions
Low phosphorus availability favors cucumber resistance to Fusarium wilt, reducing disease incidence by 62% compared to h…
Inulin-type fructans in psoriasis: body composition, carbohydrate metabolism and energy expenditure — INGUTSKIN RCT
Supplementation with 15 g/day of inulin-type fructans for 8 weeks stabilized fasting glucose in mild psoriasis patients,…
Re-evaluating gut microbiome signatures of post-antibiotic dietary fiber intake in a large adult cohort
High-fiber intake post-antibiotic did not increase alpha diversity and did not uniformly enrich commensal Clostridia; it…
Effect of pasteurized Akkermansia muciniphila MucT on insulin sensitivity, body composition, and GLP-1 production in subjects with metabolic syndrome
The primary insulin sensitivity endpoint was not met in the full intention-to-treat population; exploratory analyses sug…
Ascophyllan Supplementation: Randomized Pilot Assesses Safety and Exploratory Effects on Immunity and Gut Microbiome
In a 12-participant pilot trial, 28-day ascophyllan supplementation was safe, but no immunological, antioxidant, or micr…
Gut microbiota and diabetic retinopathy: a meta-analysis with limited findings
Patients with diabetic retinopathy show modest differences in gut microbiota composition compared to type 2 diabetics wi…