Global research trends in enteric nervous system and gut microbiota: a bibliometric analysis (2005–2025)
A bibliometric analysis of 759 publications maps growth patterns and thematic foci in the ENS–microbiota field from 2005 to 2025.
| Population | — |
|---|---|
| Intervention | — |
| Comparator | — |
| Outcome | — |
What the study showed
Annual publication volume grew in three discernible phases, peaking in recent years. The United States is the most influential country; University College Cork, McMaster University, University of Melbourne, and Baylor College of Medicine rank as top institutions. John F. Cryan is identified as the most influential author, with his microbiota-gut-brain axis review as the most cited reference.
How it was done
Publications were retrieved from Web of Science Core Collection and Scopus (2005–2025) and analysed using CiteSpace, VOSviewer, R-studio, Origin, and Excel 365.
Risk of bias
Bibliometrics does not assess methodological quality of the mapped studies; restriction to two databases may exclude relevant literature. The abstract does not detail the emerging themes identified by keyword analysis.
What this study does NOT prove
Does not demonstrate causality or the efficacy of any intervention targeting the ENS–microbiota axis.
In clinical practice
This is a descriptive study of a scientific field and generates no direct clinical recommendations.
Limitations
Bibliometrics does not assess methodological quality of the mapped studies; restriction to two databases may exclude relevant literature. The abstract does not detail the emerging themes identified by keyword analysis.
Technical appendix
Version history
- 1.0 · 2026-09-11 — Auto-generated under Evidence Standard v1.0
Paid access: structured summary from public metadata; consult the original study at the source.