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Jul 20, 2026

Fecal microbiota transplantation for post-surgical chronic constipation in an elderly patient: case report

A single elderly patient with refractory chronic constipation and surgically altered bowel anatomy showed symptomatic resolution after FMT.

Evidence levelDNarrative / animal / in vitro / mechanistic
Study typeother
Sample1
Effect directionMechanistic only
CertaintyVery low
Clinical applicabilityVery low
Overinterpretation risk1/5 · Low
PICO
Population
Intervention
Comparator
Outcome

What the study showed

The abstract reports that a 65-year-old man with prior sigmoidostomy, enterostomy, and jejunostomy and an 11-year history of refractory constipation experienced complete resolution of abdominal distension and pain within 6 months of FMT. No recurrence was observed during follow-up.

How it was done

This is a single case report with no control group. FMT was applied after failure of conventional laxatives including lactulose, castor oil, and glycerin enemas.

Risk of bias

Single case report (n=1) with no comparator group, no blinding, and no detail on FMT protocol, donor selection, or exact follow-up duration. Causality cannot be established.

Interpretation limit

What this study does NOT prove

It cannot be concluded that FMT is effective for chronic constipation in elderly patients with altered anatomy or that the observed effects are solely attributable to the intervention.

In clinical practice

This finding does not support a change in clinical practice; FMT for chronic constipation remains experimental and requires controlled trials before any recommendation.

Limitations

Single case report (n=1) with no comparator group, no blinding, and no detail on FMT protocol, donor selection, or exact follow-up duration. Causality cannot be established.

Technical appendix

Version history

  • 1.0 · 2026-07-20 — Auto-generated under Evidence Standard v1.0

Paid access: structured summary from public metadata; consult the original study at the source.

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